Symptoms of metastatic bladder cancer (2024)

Metastatic bladder cancer means that a cancer that began in the bladder has spread to another part of your body. It is also called advanced bladder cancer.

If your bladder cancer has spread you might:

  • have bone, back or tummy pain
  • feel very tired (fatigue)
  • feel generally unwell
  • have weight loss for no known reason

You might have specific symptoms depending on where the cancer has spread to. These symptoms can also be caused by other medical conditions so might not be a sign that the cancer has spread.

You should contact your doctor if you're concerned about any symptoms.

Where does bladder cancer spread?

Bladder cancer is most likely to spread to thestructures close to the bladder, such as theureters,urethra,prostate, vagin*, or into thepelvis. This is called local spread or locally advanced cancer. The ureters are the tubes which carry urine from the kidneys to the bladder. The urethra is the tube which carries urine from the bladder to the outside of the body.

Symptoms of metastatic bladder cancer (1)
Symptoms of metastatic bladder cancer (2)

Bladder cancer can also spread to another part of the body. Thisis secondary canceror metastasis. The places it's most likely to spread to are your:

  • lymph nodes in thepelvis and tummy (abdomen)
  • lungs
  • liver
  • bones
Symptoms of metastatic bladder cancer (3)
  • Read more about secondary cancer

Symptoms of locally advanced cancer

Large tumours in the bladder can press on the ureters and spread to other nearby structures. You might find that that you have:

  • problems passing urine such as difficulty weeing or frequency
  • blood in your urine
  • pain in your back
  • pain in your tummy (abdomen) or pelvis
  • problems with how well your kidneys work

Symptoms if bladder cancer has spread to your lymph nodes

Lymph nodes are part of a system of tubes and glands in the body that filters body fluid and fights infection.

There are lots of lymph nodes in the tummy (abdomen) and groin area, which is close to the bladder. Bladder cancer can spread to these, or to lymph nodes in other parts of the body.The most common symptoms are swelling and pain around the area where the cancer has spread.

Cancer cells can stop lymph fluid from draining away. This might lead to swelling in the legs due to fluid build up in that area. The swelling is called lymphoedema.

  • Read more about lymphoedema

Symptoms if bladder cancer has spread to your bones

Bladder cancer can spread to the bones.

The most common symptom if cancer has spread to the bone is bone pain. It is usually there most of the time and can wake you up at night. The pain can be a dull ache or stabbing pain.

Your bones might also become weaker and more likely to break (fracture).

  • Find out about treatment for cancer that has spread to the bones

If bladder cancer spreads to the spine, it can put pressure on thespinal cord Symptoms of metastatic bladder cancer (4) and cause spinal cord compression. This stops the nerves from being able to work properly. Back pain is usually the first symptom of spinal cord compression.

Spinal cord compression is an emergency. You should contact your treatment team immediately if you are worried you might have spinal cord compression.

  • Find out about spinal cord compression

Symptoms if bladder cancer has spread to your liver

You might have any of the following symptoms if your cancer has spread to the liver:

  • discomfort or pain on the right side of your tummy (abdomen)
  • feeling sick
  • poor appetite and weight loss
  • a swollen tummy (called ascites)
  • yellowing of the skin and whites of the eyes (jaundice)
  • itchy skin
  • Find out about treatment for cancer that has spread to the liver

Symptoms if bladder cancer has spread to your lungs

You may have any of these symptoms if cancer has spread to your lungs:

  • a cough that doesn’t go away (often worse at night)
  • breathlessness
  • ongoing chest infections
  • coughing up blood
  • a build up of fluid between the chest wall and the lung (a pleural effusion)
  • Find out about treatment for cancer that has spread to the lung

Symptom control team

There are symptom control teams in most cancer units. They are also called the palliative care team. They can help you to stay as well as possible for as long as possible. They are also in hospices and many general hospitals.

Most symptom control teams have home care services so they can visit you at home.

How you might feel

When bladder cancer has spread, it can no longer be cured. But treatment can control it for some time and help to relieve symptoms.

Finding out that your cancer can’t be cured is distressing and can be a shock. It’s commonto feel uncertain and anxious. It's normal not to be able to think about anything else.

Lots of information and support are available to you,your family and your friends. It can help to find out more about your cancer and the treatments you might have. Many people find that knowing more about their situation can make it easier to cope.

Talk to your doctor or nurseto understand:

  • what your diagnosis means
  • what is likely to happen
  • what treatment is available
  • how treatment can help you
  • Find out more about coping with metastatic bladder cancer
Symptoms of metastatic bladder cancer (2024)

FAQs

Symptoms of metastatic bladder cancer? ›

It typically doesn't spread very quickly. However, other types of bladder cancer, such as adenocarcinoma, squamous cell carcinoma, and small cell carcinoma, spread much faster. In most cases, treatment, if started early enough, can prevent the spread of bladder cancer.

How long does it take for bladder cancer to metastasis? ›

It typically doesn't spread very quickly. However, other types of bladder cancer, such as adenocarcinoma, squamous cell carcinoma, and small cell carcinoma, spread much faster. In most cases, treatment, if started early enough, can prevent the spread of bladder cancer.

What are the symptoms of late stage bladder cancer? ›

Symptoms of Advanced Bladder Cancer
  • An inability to urinate.
  • Lower back pain on one side of the body.
  • Loss of appetite.
  • Unintended weight loss.
  • Overwhelming fatigue.
  • Bone pain.
  • Swelling in the feet.

How long can you live with stage 4 bladder cancer? ›

If bladder cancer has spread to the regional lymph nodes, the 5-year survival rate is 39.2%. If it has spread to a distant site, the 5-year survival rate is 8.3%. Receiving a diagnosis of stage 4 bladder cancer can feel overwhelming.

What stage of bladder cancer has blood in urine? ›

Usually, the early stages of bladder cancer (when it's small and only in the bladder) cause bleeding but little or no pain or other symptoms. Blood in the urine doesn't always mean you have bladder cancer.

Where does bladder cancer metastasize to first? ›

Conclusion: Lymph nodes, bones, lung, liver, and peritoneum are the most common sites of metastasis from bladder cancer. Tumors in a more advanced T category and those with atypical histologic features metastasize earlier.

Where is the first place bladder cancer spreads? ›

Where can bladder cancer spread to? Not all bladder cancers will spread. But If it does it's most likely to spread to the structures close to the bladder, such as the ureters, urethra, prostate, vagin*, or into the pelvis. This is called local spread.

What is the red flag for bladder cancer? ›

Blood in the urine is the most common symptom of bladder cancer. Around 80 out of 100 people with bladder cancer (around 80%) have some blood in their urine. Doctors call blood in the urine haematuria (pronounced heem-at-you-ree-ah). You may see the blood in your urine.

What is the biggest symptom of bladder cancer? ›

The most common symptom is blood in the urine, called hematuria. It's often slightly rusty to bright red in color. You may see blood in your urine at one point, then not see it again for a while. Sometimes there are very small amounts of blood in the urine that can only be found by having a test done.

What hurts when you have bladder cancer? ›

Pain in flank, the section of the back between the ribs and the hip bone. Painful urination. Frequent urination. Urinary hesitancy, or difficulty beginning to urinate.

What to expect when dying from bladder cancer? ›

The dying person will feel weak and sleep a lot. When death is very near, you might notice some physical changes such as changes in breathing, loss of bladder and bowel control and unconsciousness. It can be emotionally very difficult to watch someone go through these physical changes.

What are the odds of beating bladder cancer? ›

If the cancer is just on the inner lining of the bladder (stage 0 or carcinoma in situ), the 5-year survival rate is about 98%. If the cancer is growing just beyond the inner lining into the bladder wall, but is still just in the bladder (Stage I), the 5-year survival rate is about 88%.

Can you have bladder cancer for years and not know it? ›

Can bladder cancer go undetected for years? If symptoms such as blood in the urine and changes in urinary habits are ignored by an individual and/or repeatedly misdiagnosed, it's possible that bladder cancer may not be detected for months or, in some cases, even years.

What is the most common first symptom of a malignant tumor of the bladder? ›

For most people, the first symptom of bladder cancer is blood in the urine, also called hematuria.

Do you feel unwell with bladder cancer? ›

If your bladder cancer has spread you might: have bone, back or tummy pain. feel very tired (fatigue) feel generally unwell.

What are the symptoms of stage 3 bladder cancer? ›

Stage 3 bladder cancer symptoms
  • inability to urinate.
  • appetite loss.
  • weight loss.
  • lower back pain.
  • weakness and fatigue.
  • swelling of your feet.
  • bone pain.

How likely is bladder cancer to metastasize? ›

It's not uncommon for bladder cancer to metastasize to the lungs, liver or bones. This can cause pain and other symptoms in distant parts of the body. In many cases, metastatic bladder cancer also causes general complications such as fatigue and weight loss.

How long can you live with bladder cancer that has spread? ›

5-year relative survival rates for bladder cancer
SEER Stage5-year Relative Survival Rate
In situ alone Localized96% 71%
Regional39%
Distant8%
All SEER stages combined78%
Jan 17, 2024

Is bladder cancer a fast or slow growing cancer? ›

Knowing the grade helps your doctors work out the best treatment plan for you: low grade – the cancer cells are usually slow-growing. Most bladder tumours are low grade. high grade – the cancer cells look very abnormal and grow quickly.

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