How Do Doctors Find Bladder Cancer? (2024)

Bladder cancer is something that impacts many individuals and families every year. Similar to other forms of cancer, the earlier bladder cancer is detected, the faster the treatment process can begin. Learn more about bladder cancer diagnosis below and reach out to a healthcare professional with any questions or concerns.

How Do Doctors Detect Bladder Cancer?

There are several tests that doctors may use to diagnose bladder cancer. They include:

Urinary Screening

One of the most common symptoms of bladder cancer is blood in the urine. There are numerous reasons why you might have blood in your urine, so your doctor test your urine.

Specifically, the doctor may run a urine cytology scan. This scan is done to see if there are any abnormal cells present in your urine. While it’s not common, sometimes if the doctor spots something unusual, he or she may use a microscope or perform a molecular analysis to see if there are any tumor cells in the urine.

Cystoscopy

How Do Doctors Find Bladder Cancer? (1)

A cystoscopy is one of the most important diagnostic procedures for bladder cancer. The doctor will use a long thin camera that is inserted through the urethra and into the bladder to see if there any growths present. If a doctor spots something unusual, he or she may decide to perform a biopsy to confirm the diagnosis. While a cystoscopy may spot something unusual, it is difficult to confirm the diagnosis without getting a piece of the growth. Watch our video on cystoscopy.

Biopsy

A biopsy involves removing a small piece of the growth for further examination and testing. If a tumor or other abnormality is identified, the urologist will likely schedule you for a cystoscopy under anesthesia with bladder biopsy. During the biopsy procedure, the doctor will remove a piece of the tumor and send it to the lab for analysis by a pathologist. The doctor may want to take multiple biopsies to make sure he or she gets an accurate picture of the entire growth. Watch our video about biopsies.

After this, the doctor may decide to perform a transurethral resection of the bladder tumor, or TURBT. During this procedure, the doctor will try to remove as much of the tumor as possible through the urethra. The doctor may use tools attached to a resectoscope to remove the tumor tissue.. Then, the tumor will be sent to the pathologist for further testing.

Your doctor may also run additional tests to look at other parts of your urinary tract.

Radiological Test: What is a CT Urogram?

TheCT urogramis a radiological test to explore possible reasons for blood in the urine or other symptoms. This specialized scan uses intravenous (IV) contrast (a substance used to enhance the visibility of internal structures in X-ray based imaging). A CT urogram examines the upper urinary tract (kidneys and ureters) in detail.

This test is good at finding tumors of the kidney, renal pelvis, and ureter, as well as other urologic abnormalities. It may identify kidney stones and hydronephrosis (swelling of the kidney that is often due to downstream blockage). In addition, the entire abdomen and pelvis is also imaged. This allows a radiologist to identify other abnormalities in these parts of the body. In patients with cancer, it will help identify signs of spread to lymph nodes or other organs like the liver.

Your healthcare provider will request blood work to see if you have normal kidney function before you can receive the contrast required for a CT urogram. If the contrast cannot be given, your doctor may decide to perform a CT scan without contrast or other imaging study. A procedure called cystoscopy with retrograde pyelograms may be suggested. The urologist performs x-rays while injecting dye into the ureters. Like a CT urogram, it can help to identify abnormalities of the ureter and renal pelvis.

While some bladder tumors may be found on a CT urogram or other imaging test, others will not. A urologist will often recommend a cystoscopy to evaluate the lower urinary tract (bladder/urethra) for a source of blood in the urine or to workup other urologic symptoms.

What is a MR Urogram?

Another option for imaging is MRI of the abdomen and pelvis or MR Urogram. This test is also effective at finding tumors in the kidney and ureters and evidence of spread of cancer. It may be used to avoid radiation or in patients with contrast dye allergies or borderline kidney function. It is not quite as good at finding kidney stones and similar to CT urogram may miss tumors in the bladder such that patients still require cystoscopy.

What is Renal Ultrasound?

Renal ultrasound is the least invasive way to evaluate the kidneys. It does not require radiation and avoids contrast. It may be used in lower risk patients and those with contrast allergies or poor renal function. Unfortunately, it can miss small kidney stones and tumors. Also, it will not detect tumors in the ureter unless they are causing a blockage leading to hydronephrosis.

Frequently Asked Questions (FAQs)

Some of the most common questions people ask include:

What are the first symptoms of bladder cancer?

Some of the most common initial symptoms include blood in the urine, pain while urinating, urinating more frequently, and back pain.

Can bladder cancer be diagnosed using a CT scan alone?

A CT scan is useful in staging bladder cancer because it can identify unusual growth, but it is impossible to diagnose bladder cancer without placing a piece of the growth under a microscope.

Does a cystoscopy hurt?

A cystoscopy should not be painful. Typically, the patient is awake during the procedure, but local anesthesia might be given.

Click here to read ourGet the Facts | Cystoscopy (PDF), filled with advice from patients who have experienced it.

How Do Doctors Find Bladder Cancer? (2024)

FAQs

How Do Doctors Find Bladder Cancer? ›

The most common way is to look at the cells under a microscope, called urinary cytology. There are other urine tests using molecular analysis that can be done to help find cancer, usually at the same time as urinary cytology. Cystoscopy. Cystoscopy is the key diagnostic procedure for bladder cancer.

How do doctors detect bladder cancer? ›

A sample of your urine is analyzed under a microscope to check for cancer cells in a procedure called urine cytology. Imaging tests. Imaging tests, such as computerized tomography (CT) urogram or retrograde pyelogram, allow your doctor to examine the structures of your urinary tract.

What is the most reliable test for detecting bladder cancer? ›

Pathology Tests

The most efficient, noninvasive and inexpensive test is a urinalysis/cytology.

Which is most accurate diagnostic method for bladder cancer? ›

If bladder cancer is suspected, a biopsy is needed to be sure of the diagnosis. The procedure used to biopsy an abnormal area is a transurethral resection of bladder tumor (TURBT), also known as just a transurethral resection (TUR).

What is the number one symptom of bladder cancer? ›

The most common symptom is blood in the urine, called hematuria. It's often slightly rusty to bright red in color. You may see blood in your urine at one point, then not see it again for a while. Sometimes there are very small amounts of blood in the urine that can only be found by having a test done.

What shows in urine if you have bladder cancer? ›

Tests for bladder cancer look for different substances and/or cancer cells in the urine. Urinalysis: One way to test for bladder cancer is to check for blood in the urine ( hematuria). This can be done during a urinalysis, which is a simple test to check for blood and other substances in a sample of urine.

When should you suspect bladder cancer? ›

Bladder cancer symptoms are usually clear and easy to notice. If any of these symptoms are present, it may be worth making an appointment to see a doctor: Blood in the urine, frequent urination, painful urination or back pain.

What is the gold standard for diagnosing bladder cancer? ›

The most common way is to look at the cells under a microscope, called urinary cytology. There are other urine tests using molecular analysis that can be done to help find cancer, usually at the same time as urinary cytology. Cystoscopy. Cystoscopy is the key diagnostic procedure for bladder cancer.

What are the odds of beating bladder cancer? ›

The 5-year relative survival rate of people with bladder cancer that has not spread beyond the inner layer of the bladder wall is 96%. Almost half of people are diagnosed with this stage. If the tumor is invasive but has not yet spread outside the bladder, the 5-year relative survival rate is 70%.

What mimics bladder cancer? ›

The symptoms of urinary tract infections (UTIs) and the symptoms of bladder cancer can be very similar. Both may involve pain while urinating, a feeling of urgency, frequent urination, and the presence of white or red blood cells in the urine.

What labs are elevated with bladder cancer? ›

BTA tests (looks for bladder tumor-associated antigen—BTA—which is also known as CFHrp) ImmunoCyt™ (looks for mucin and carcinoembryonic antigen substances that are frequently found on cancer cells) NMP22 BladderChek® (looks for NMP22—nuclear matrix protein 22—which is often elevated in bladder cancer patients)

What does Stage 1 bladder cancer feel like? ›

The first sign of bladder cancer is blood in the urine, which is painless for most people. In the early stages, this may be your only symptom, though some people don't experience it. Other symptoms include changes in bladder habits, frequent urinary infections, and pelvic or back pain, which might be on one side.

What is life expectancy with bladder cancer? ›

If the cancer extends through the bladder to the surrounding tissue or has spread to nearby lymph nodes or organs, the five-year survival rate is 39%. If the cancer has spread to distant parts of the body, the five-year survival rate is 8%. About 4% of people are diagnosed at this stage.

What is the red flag for bladder cancer? ›

Blood in the urine is the most common symptom of bladder cancer. Around 80 out of 100 people with bladder cancer (around 80%) have some blood in their urine. Doctors call blood in the urine haematuria (pronounced heem-at-you-ree-ah). You may see the blood in your urine.

Where do you hurt with bladder cancer? ›

These include: Blood in the urine, known as hematuria. Frequent urinary tract infections. Pain in flank, the section of the back between the ribs and the hip bone.

Do you feel ill with bladder cancer? ›

Symptoms of advanced bladder cancer

Being unable to urinate. Lower back pain on one side. Loss of appetite and weight loss. Feeling tired or weak.

Does bladder cancer show up in urine test? ›

Urine testing can assist in diagnosing many different disorders including kidney disease, diabetes, liver disorders, urinary tract infections (UTIs), and bladder cancer.

Will blood work show bladder cancer? ›

Tests to Diagnose Bladder Cancer

Blood test: Blood samples are used to measure certain substances released into the blood by organs and tissues in the body. An unusual amount of a substance (higher or lower than normal) can be a sign of disease in the organ or tissue that makes it.

How is bladder cancer detected early? ›

Bladder cancer is typically diagnosed by going through the patient's health history and checking for physical signs of the disease. A urine sample may also be taken and checked for abnormal cells.

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